Clinical Outcomes for Single Isocenter Treatments in Patients with up to 10 Metastases


Giuseppe Minniti, MD, from UPMC San Pietro Fatebenefratelli discusses their clinical outcomes for single isocenter treatments in patients with up to 10 metastases. He begins by talking about radiosurgery (SRS) for brain metastases, including how many can be treated. He then discusses single-isocenter multi-target DCA SRS in detail, delving into dosimetric characteristics of treatments, clinical outcome (local control and radiation-induced brain necrosis), accuracy of positioning and evaluation of target coverage.


Video Transcript

Thank you for the introduction. And okay, I will talk about the clinical outcomes for single isocenter radiosurgery in patients with up to 10 brain mets. So this is the outline. I will touch mainly two questions, why we should use radiosurgery for patients with up to 10 mets and how effective and safe is new techniques, single-isocenter techniques compared with single-target radiosurgery. So we know that radiosurgery is the recommended treatment for a limited number of mets, usually four or five. This is basically based on the fact that whole-brain radiation therapy doesn't give an additional survival to patients...

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