Hypo-fractionated stereotactic radiosurgery management of large arteriovenous malformations


Jan Boström, MD, from the University Hospital of Bonn (UKB), Germany, discusses the use of hypo-fractionated stereotactic radiosurgery for the management of large arteriovenous malformations (AVMs). He begins by outlining the goal of AVM treatment: The complete obliteration of the nidus. He then discusses the lessons they’ve learned at his institution in terms of optimal dose, ideal volume, maximum volume and radionecrosis when treating with stereotactic radiosurgery. He then provides case examples of patients with AVMs treated with single session radiosurgery, staged radiosurgery and hypofractionated stereotactic radiotherapy. He then discusses the study that was published in conjunction with these findings titled “Treatment of Cerebral Arteriovenous Malformations with Radiosurgery or Hypofractionated Stereotactic Radiotherapy in a Consecutive Pooled Linear Accelerator Series” and the results that were determined therein.


Video Transcript

At first, thank you, Reinhardt, for our invitation and I take it everyone in the audience knows that normally this is your special topic. The main goal should always be the complete obliteration of the AVM nidus. And we have some important lessons learned from one session radiosurgery. And we know something about the optimal dose, this is not only true for Gamma Knife radiosurgery but also for Linac radiosurgery, something between 18 and 20 Gy. We have some lessons learned about the ideal volume. If we treat small volume AVMs around 5 cubic centimeters, we see rarely complications like...

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