Stereotactic Treatment of Brain Metastases with the Novalis in Medical Center Haaglanden: Relationship Between Volume, Dose and Local Control


Antoinette Verbeek-de Kanter of the Medical Center Haaglanden discusses stereotactic treatment of brain metastases with Novalis at Medical Center Haaglanden and the relationship between volume, dose and local control. She begins with a short history of radiotherapeutic treatment of brain metastases and studies that analyze the use of stereotactic radiotherapy (SRT) after whole brain radiation therapy (WBRT), radiosurgery alone as well as neurosurgery. She gives a detailed description of the radiosurgery treatment procedure at her institution, including contouring the tumor, dose prescription, procedure planning, localization and verification with ExacTrac Patient Positioning. She then gives an in depth look at the patient demographics, side effects, and overall results of treatment. She concludes that the higher the volume, the lower the dose and the less local control.

About the speaker

Antoinette Verbeek-de Kanter

Antoinette Verbeek-de Kanter
Medical Center Haaglanden, Netherlands


Video Transcript

First of all, I'd like to thank the organizing committee for the opportunity to present our results of stereotactic radiotherapy treatment for brain metastasis in the Medical Center Haaglanden. Before I present the results, first a little history. Before the era of stereotactic radiotherapy, brain metastases were treated with fractionated whole-brain radiotherapy. The first step was adding stereotactic radiotherapy, and because it demonstrated survival benefit, the question arose whether whole-brain radiotherapy could be emitted. Role of stereotactic radiotherapy after whole-brain radiotherapy is a subject of the RTOG 95-08 and published by Andrews. He concluded that adding stereotactic radiotherapy improved local...

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