Treatment Response Assessment and Retreatment Decision Making

Event: 8th International Conference of the Novalis Circle 2018
Topic: Intracranial metastasis
Year: 2018

Diana Horvath-Rizea, MD, from the Clinic for Neuroradiology at Klinikum Stuttgart, Germany, discusses treatment response assessment and re-treatment decision-making using Brainlab Elements Contrast Clearance Analysis. She describes how the methodology works by subtracting an early from a late T1 scan from which the Contrast Clearance Analysis image is generated. She then compares Contrast Clearance Analysis to perfusion MRI, discussing specificity and sensitivity. Finally, she provides case examples from her institution to demonstrate the methodology and results.

Video Transcript

So I'd like to introduce you the Contrast Clearance Analysis to differentiate between Treatment Response and Tumor Progression. This is still a problem and a challenge every day for us radiologists to see this followup after treatment. So we see the first one after treatment, then, two months later. And then another month later, this very high enhancement in this area after treatment. So what is it? And looking at the T1 on the first line, you see it's just the same to recruitment. But two weeks later, you see this blue area on this side. So with Contrast Clearance...

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