Ausaf Bari, MD, Neurosurgeon at UCLA Medical Center discusses fibertracking and its use in stereotactic radiosurgery (SRS) as well as cranial nerve imaging that has been done at his institution. He addresses the need in medical imaging for patient-specific connectivity information and outlines the use of connectivity-based imaging using diffusion tensor imaging and tractography to delineate nerve fibers, such as the trigeminal nerve and optic pathway, for targeting. With the support of case examples, he then delves into applying this principle to radiosurgical thalamotomies and demonstrates how connectivity impacts efficacy.